With more than 500,000 installations TYPO3 is the most widely used Enterprise Content Management System, providing the basis for websites, intranets and mobile applications. TYPO3 enables customers all over the world to run and extend their applications according to their business needs.
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A CMS will sometimes include a meta tag within the html of each page. This is usually a "generator" tag like <meta name="generator" content="What CMS" /> but could also be "application-name", "Powered-By" or anyting else the CMS creators decide to use.
If a CMS doesn't have meta tags, it will often have other uniquely identifiable html markup. This can range from unique html comments, ids or classes.